About MQT v1

The Multimodal Query Tool (MQT) is a self-service tool designed to empower all researchers to:

  • Quickly assess data fit for a research question or proposed analysis by building and visualizing custom multimodal datasets in real time
  • Easily search and access a large volume and variety of multimodal data on ADRC participants across major AD/ADRD repositories (e.g., NACC, NCRAD, NIAGADS, ADKP, LONI, and others)
  • Monitor sample size and key characteristics of eligible participants as you refine your query criteria
  • Download NACCIDs for your selected participants and use them to access additional data across NACC and partner repositories
  • Generate a reproducible query record to cite in publications and support transparent, FAIR-aligned research

NOTE: MQT v1 is a prototype release undergoing validation and continued development. Minor discrepancies may exist between searchable data in MQT and the most recent Quick Access File (QAF). These will eventually be resolved when the QAF is migrated to the new NACC Data Platform. Questions? Submit a support form.

Multimodal Query Tool Figure

How to Use the MQT V1

  1. Set your filters to define participant selection criteria.
  2. Run multiple queries as needed (e.g., for case/control groups).
  3. Download NACCIDs for participants who meet your criteria.
  4. Record your filters to create a reproducible selection record for manuscripts (your filters appear in the filter summary section).
  5. Request full datasets through the Quick Access File Data Request System. You’ll need to sign a DUA to access data across multiple modalities.
  6. Use your statistical software to restrict the Quick Access File to your selected participants.
  7. Use your “shopping list” (NACCID list) to streamline access to additional data modalities from partner repositories (e.g., NCRAD, NIAGADS, ADKP, LONI).

Upcoming Features

  • Expanded filtering options for additional data modalities—including those housed at partner repositories—such as expanded neuropathology data, fluid biomarker and genomic/genetic data availability and analysis results, and up-to-date biospecimen inventories.
  • Time-based filtering, allowing researchers to refine queries based on intervals between events (e.g., time between a clinical visit, blood draw, and PET exam).
  • Streamlined access workflows to simplify requesting and retrieving data from partner repositories linked to NACC.

Share Your Feedback

Dozens of AD/ADRD researchers provided guidance on this first release. Your input will help us further refine the tool and prioritize new features. Help us shape the future of the MQT!

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