About NACC

The National Alzheimer’s Coordinating Center (NACC) functions as the centralized data repository, and collaboration and communication hub for the National Institute of Aging’s (NIA’s) Alzheimer’s Disease and Research Centers (ADRC) Program, which currently includes 33 centers and 4 exploratory centers across the United States.

The National Alzheimer's Coordinating Center was established in 1999 by the National Institute on Aging/NIH to facilitate collaborative research. Using data collected from NIA-funded Alzheimer's Disease Research Centers (ADRCs) across the United States, NACC has developed and maintains a large relational database of standardized clinical and neuropathological research data. In partnership with the Alzheimer's Disease Genetics Consortium (ADGC), the National Centralized Repository for Alzheimer's Disease and Related Disorders (NCRAD), and the NIA Genetics of Alzheimer's Disease Data Storage Site (NIAGADS), NACC provides a valuable resource for both exploratory and explanatory Alzheimer's disease research. NACC data are freely available to all researchers.

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NACC is located in the Department of Epidemiology at the University of Washington in Seattle and funded by NIA/NIH cooperative grant U24 AG072122.

The ADRC program

The National Institute on Aging/NIH currently funds 33 ADRCs and 4 Exploratory Centers across the United States. The Centers work to translate research advances into improved diagnosis and care and find ways to treat and possibly prevent Alzheimer's disease and related dementias. Each has its own research focus and recruitment protocol. However, the Centers are all required to involve their entire clinic enrollment in the Uniform Data Set (UDS) study and submit these data to NACC.

The Centers are organized in "cores" (Administrative; Clinical; Data Management & Statistics; Imaging; Neuropathology; Outreach, Recruitment and Engagement; and Biomarker) and "components" (Research Education Component).

For more information on the ADRC Program, please visit the NIA website.

NACC Modernization

NACC relationships with ADRCs, SCAN, NCRAD, ADGC & NIAGADs, NACC and investigators

Help us build a one-stop-shop for all data from the Alzheimer’s Disease Research Centers (ADRC) Program

NACC , NCRAD, and NIAGADS are eager to partner with ADRD researchers and clinicians from across the Alzheimer’s Disease Research Centers (ADRC) Program and beyond to build the “Data Front Door” (DFD), a one-stop-shop for all ADRC data. Our goal is to have this platform integrate and connect all ADRC data streams to NACC IDs and serve as an effective search, visualization, and access interface for this data. NCRAD and NIAGADS data will continue to be housed within the NCRAD and NIAGADS databases but biomarker and genetic metadata for all ADRC participants will be searchable through the DFD.

Our hope is that harmonizing these data streams and connecting them to NACC IDs will enable researchers to investigate and answer new questions in Alzheimer’s disease.

We welcome you to share your input in two ways:

  1. Sign-up to participate in one of our focus groups with thought leaders from across the ADRC program
  2. Take the survey on Data Front Door Requirements

NACC staff

Leadership Team

Walter A. Kukull, PhD
  • Walter A. Kukull, PhD
  • He/Him
  • Principal Investigator/Director
  • Professor, Epidemiology
  • (206) 543-4560, (206) 616-1765
  • kukull@uw.edu
  • Walter A. Kukull, PhD

    Principal Investigator/Director

    Walter A. Kukull, PhD

    Dr. Kukull's research is focused on the neurodegenerative, vascular and other conditions causing dementia and cognitive impairment. These conditions include Alzheimer's disease, Parkinson's/Lewy body disease, frontotemporal lobar degeneration, and cerebrovascular disease. Since 1999, he has served as Director and PI of the National Alzheimer's Coordinating Center [U24 AG072122], an effort to collect and make available to researchers standardized, detailed clinical data from the approximately 37 NIA-funded Alzheimer Disease Centers across the United States. Dr. Kukull works closely with the leadership of the ADRCs and the National Institute on Aging to ensure that scientifically relevant and valid data are obtained and available from NACC’s database to any researcher anywhere.

    In addition to NACC work, he is an investigator with a number of other NIH grants. He is an elected Fellow of: American College of Epidemiology, American Academy of Neurology and American Association for Advancement of Science.

Sarah Biber, PhD
  • Sarah Biber, PhD
  • She/Her
  • Executive Director
  • biber@uw.edu
  • Sarah Biber, PhD

    Executive Director

    Sarah Biber, PhD

    Dr. Sarah Biber is the Executive Director for the National Alzheimer’s Coordinating Center (NACC), based at the University of Washington. NACC serves as the data, communication, and collaboration hub for NIA’s National Alzheimer’s Disease Research Centers (ADRC) Program, comprised of 33 centers across the United States. NACC is home to one of the largest (48,600+ participants), oldest, and most powerful AD/ADRD datasets, and is currently funded by more than $50M in NIA grants. Dr. Biber co-leads NACC’s strategic and scientific direction in collaboration with NACC’s PI and Director, Dr. Walter Kukull. Within this role, she represents NACC with national partners, spearheads national initiatives, leads academic and industry partnerships, and oversees NACC’s tech, operations, research, communications, and grants and finance teams. She has a PhD in molecular and cellular biology and extensive experience leading strategy for complex centers and programs focused on advancing research and innovation.

    Prior to joining NACC in November 2021, Dr. Biber led the Surgical Innovation Program at Oregon Health and Science University (OHSU) where she shaped and significantly expanded the department of surgery’s innovation capacity and footprint, co-developed surgical innovations, led academic and industry partnerships, and founded the OHSU Invent-a-thon. She previously served as the Assistant Director for NIH’s National Center for Data to Health (CD2H), where she was instrumental in launching the center and led operations to advance informatics innovation, data sharing, software development, and collaboration across the 50+ Clinical Translational Science Awards Program Centers. Prior to CD2H, she was Entrepreneurial Program Director at the Oregon Bioscience Incubator where she helped grow the incubator three-fold and spearheaded statewide partnerships to advance entrepreneurship and startups, served on state-wide committees, and co-founded Accelerate Biotech and Digital Health PDX.

Operations Team

Jessica Welsch, MBA
  • Jessica Welsch, MBA
  • She/Her
  • Senior Project Manager
  • jmwelsch@uw.edu
Hannah Rosentreter
  • Hannah Rosentreter
  • She/Her
  • Manager of Special Projects
  • hanrose3@uw.edu
Brittany Fair, MS
  • Brittany Fair, MS
  • She/Her
  • Manager of Communications
  • (650) 804-5219
  • bfair@uw.edu
Amy Young
  • Amy Young
  • She/Her
  • Public Information Specialist
  • (206) 708-5528
  • ayoung1@uw.edu
Brittany Hale
  • Brittany Hale
  • She/Her
  • Project Manager
  • halebri@uw.edu
Valerie Hockens
  • Valerie Hockens
  • Program Operations Specialist
  • (206) 616-6264
  • vhockens@uw.edu
Faith Buckley, M.B.A., M.S.
  • Faith Buckley, M.B.A., M.S.
  • She/Her
  • Administrative Specialist
  • (503) 750-4012
  • fbuckley@uw.edu
Aileen Ida, MA
  • Aileen Ida, MA
  • She/Her
  • Communications Specialist
  • ailida@uw.edu
Jane Xia, MHA
  • Jane Xia, MHA
  • She/Her
  • Grants & Finance Team Manager
  • jxia2@uw.edu
Emily Almeda
  • Emily Almeda
  • She/Her
  • Administrative Coordinator
  • ealmeda@uw.edu
Tina Monroe
  • Tina Monroe
  • She/Her
  • Human Resources Specialist
  • tmonro@uw.edu

Research Team

Kari A. Stephens, PhD
  • Kari A. Stephens, PhD
  • She/Her
  • Associate Director
  • Associate Professor, Director of Clinical Research Informatics, Department of Family Medicine
  • Adjunct Associate Professor, Department of Biomedical Informatics and Medical Education
  • (206) 221-0349
  • kstephen@uw.edu
Charles Mock, MD, PhD, FACS
  • Charles Mock, MD, PhD, FACS
  • He/Him
  • Associate Director and Epidemiologist
  • Professor, Epidemiology
  • Global Health, Surgery
  • (206) 543-6944
  • cmock@uw.edu
Dean K. Shibata, MD
  • Dean K. Shibata, MD
  • He/Him
  • Co-investigator and Radiologist
  • Professor, Radiology
  • (206) 543-8637
  • shibatad@uw.edu
Kwun Chuen Gary Chan, PhD
  • Kwun Chuen Gary Chan, PhD
  • He/Him
  • Associate Director
  • Professor, Biostatistics
  • Professor, Department of Health Systems and Population Health
  • (206) 685-9177
  • kcgchan@uw.edu
Yen-Chi Chen, PhD
  • Yen-Chi Chen, PhD
  • He/Him
  • Co-investigator and Statistician
  • Assistant Professor, Statistics
  • (206) 543-6944
  • yenchic@uw.edu
KYLE ORMSBY, PHD
  • KYLE ORMSBY, PHD
  • Co-investigator
  • Visiting Associate Professor, Mathematics
  • ormsbyk@uw.edu
Heather O'Connell
  • Heather O'Connell
  • CLARiTI Program Manager
  • oconh@uw.edu
Stacy Oswald, MHSM
  • Stacy Oswald, MHSM
  • She/Her
  • Research Operations Manager
  • oswalds2@uw.edu
Jessica Culhane, MS
  • Jessica Culhane, MS
  • She/Her
  • Research Scientist
  • (206) 616-0254
  • culhane@uw.edu
Kathryn Gauthreaux, MS
  • Kathryn Gauthreaux, MS
  • She/Her
  • Research Scientist
  • (206) 616-5647
  • kgaut@uw.edu
Zack Miller, BS
  • Zack Miller, BS
  • He/Him
  • Research Consultant
  • (206) 616-6263
  • zmiller3@uw.edu
Sarah Yasuda
  • Sarah Yasuda
  • Research Assistant
  • sarahya@uw.edu

Technology Team

Sean Mooney, PhD
  • Sean Mooney, PhD
  • He/Him
  • Associate Director
  • Chief Research Information Officer, UW Medicine
  • Professor, Department of Biomedical Informatics and Medical Education
  • (206) 685-0249
  • sdmooney@uw.edu
Janene Hubbard, BS
  • Janene Hubbard, BS
  • She/Her
  • Research Consultant
  • Research IT, UW Medicine
  • (206) 668-9582
  • janene@uw.edu
Ben Keller, PhD
  • Ben Keller, PhD
  • He/Him
  • Technology Lead
  • Research IT, UW Medicine
  • (206) 668-9599
  • bjkeller@uw.edu
Zach Stark, BBA
  • Zach Stark, BBA
  • He/Him
  • Software Engineer
  • Research IT, UW Medicine
  • (206) 668-9580
  • zstark@uw.edu
Joylee Wu, MS
  • Joylee Wu, MS
  • She/Her
  • Database Administrator
  • Research IT, UW Medicine
  • (206) 668-9583
  • joyleewu@uw.edu
Laura McLeod
  • Laura McLeod
  • She/Her
  • Senior REDCap Administrator
  • Research IT, UW Medicine
  • (206) 668-9623
  • mcleod42@uw.edu
Chandima HewaNadungodage, PhD
  • Chandima HewaNadungodage, PhD
  • She/Her
  • Software Engineer
  • Research IT, UW Medicine
  • chandhn@uw.edu
Brendan Smith, BS
  • Brendan Smith, BS
  • He/Him
  • Web Developer
  • Research IT, UW Medicine
  • brendan2@uw.edu